[Functional activity of monoclonal and monospecific antibodies in the interaction with antigenic sites of influenza virus hemagglutinin].
Identifieur interne : 002E25 ( Main/Exploration ); précédent : 002E24; suivant : 002E26[Functional activity of monoclonal and monospecific antibodies in the interaction with antigenic sites of influenza virus hemagglutinin].
Auteurs : E I Isaeva ; Z I Rovnova ; R Ia PodcherniaevaSource :
- Voprosy virusologii [ 0507-4088 ]
Descripteurs français
- KwdFr :
- MESH :
English descriptors
- KwdEn :
- MESH :
- chemical , immunology : Antibodies, Antibodies, Monoclonal, Antigens, Viral, Hemagglutinins, Viral.
- chemical : Hemagglutinin Glycoproteins, Influenza Virus, Immune Sera.
- Neutralization Tests.
Abstract
Monospecific antibodies to three nonoverlapping sites of influenza A/Singapore/1/57 (H2N2) virus isolated from hyperimmune serum by specific adsorption were characterized by capacity to inhibit virus hemagglutination, immunochemically interact with hemagglutinin, and neutralize the virus (6-7.5 lg). Monoclonal antibodies to the same virus hemagglutinin displayed an even higher activity than monospecific antibodies in serological and immunochemical tests and were characterized by a rather low (1.0-4.5 lg) or null activity in biological neutralization of the virus.
PubMed: 7740785
Affiliations:
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Le document en format XML
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Monoclonal antibodies to the same virus hemagglutinin displayed an even higher activity than monospecific antibodies in serological and immunochemical tests and were characterized by a rather low (1.0-4.5 lg) or null activity in biological neutralization of the virus.</div></front></TEI><affiliations><list></list><tree><noCountry><name sortKey="Isaeva, E I" sort="Isaeva, E I" uniqKey="Isaeva E" first="E I" last="Isaeva">E I Isaeva</name><name sortKey="Podcherniaeva, R Ia" sort="Podcherniaeva, R Ia" uniqKey="Podcherniaeva R" first="R Ia" last="Podcherniaeva">R Ia Podcherniaeva</name><name sortKey="Rovnova, Z I" sort="Rovnova, Z I" uniqKey="Rovnova Z" first="Z I" last="Rovnova">Z I Rovnova</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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